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Diet and Associated Health: Facts, Opinions and Somewhere In Between

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This came out yesterday from the CDC... just pathetic. Over 70% of Americans now are either overweight or obese, with 40% obese.



It is easy to visually confirm this - just go to any public gathering, Walmart, etc. Huge, fat guts everywhere. It is very sad.

Yea I've noticed that a lot lately. Being an old pervert just ain't as fun as it used to be.
 
Yea I've noticed that a lot lately. Being an old pervert just ain't as fun as it used to be.

Are you saying being an old pervert isn’t as fun as being a young pervert? I’m sure Tim will agree with you.


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I don’t really see the link in the study by which human consumption of sugar is proven to stimulate or accelerate cancer growth... one quote in your posted article, “Victoria Stevens, a researcher for the American Cancer Society (who had no involvement in the study) was cautious of the results, quoted by USA Today as saying, “They are providing a potential way [the Warburg effect] could be a cause of cancer, but they are a long way away from saying this could actually happen.” However, she did say the research was, “a start.”... I absolutely agree that not much good can come from not eating real food in moderation, and many things in boxes, bags, wrappers and cans are not real food. Just read the label. The study is a great step in better understanding the devil called cancer for sure.


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Here is an excellent summary with many links to related scientific papers about the mitochondrial effects of a ketogenic diet by cardiologist Dr. Gabriela Segura, MD: http://www.drmyhill.co.uk/wiki/Ketogenic_diet_-_a_connection_between_mitochondria_and_diet

I really like this diagram showing the major impacts of a ketogenic lifestyle on a variety of metabolic disorders. Many people don't believe me when I suggest keto positively impacts all these things - it almost sounds too good to be true!

Ketogenicejcn2013116f1.jpg
 
Great piece by prominent U.K. cardiologist Dr. Aseem Mahotra today about how we got to the current sorry state of bad medical science pertaining to metabolic diseases: https://www.theguardian.com/healthc...e-trumps-patients-uk-healthcare-needs-inquiry

Excerpt:
During a recent keynote lecture at the British Association for Cardiovascular Prevention and Rehabilitation annual conference, I gave the example of a man who had had a heart attack and been given statins and whose months of disabling muscle pain resolved within a week of stopping taking them. His elation was cut short when his GP told him he must never stop his statin or he could die. When the audience was asked to guess what his risk of death was from stopping the pill for two weeks, the first response was 25%. There were gasps when I revealed it was actually between zero and one in 10,000.


Such statistical and health illiteracy, far from being the exception, is actually the norm. The majority of healthcare professionals seem unable to understand medical literature. One study revealed 70% of those on a training programme failed a simple test on their understanding of evidence-based medicine


Here's an interesting thing that cardiologist Dr. William Davis (of Wheat Belly fame) had to say last week: http://www.wheatbellyblog.com/2017/...-warner-president-american-heart-association/
 
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Keto Fuel at superbodyfuel.com. A powdered food, just add olive oil, the MCT powdered oil is already in there. Short of calorie restriction, this is the best thing I've found for weight stability and being kind to your pancreas. And I feel better than the days when I would run a 10k and then drink Guiness to celebrate. The biggest impediment to success is the American convenience store, dispensers of fuel outside and sugar inside.
 
Last March I stumbled across this thread and decided to try the experiment. This morning I had my annual and reviewed the numbers from the blood test. Pretty amazing. Substantial improvement in virtually all numbers plus a 23 lb weight loss. Remarkable. My glucose has dropped and is now at 108--the top of normal. Best of all no acid reflux and falling asleep after a lunch. All in all a worthwhile change in eating habits. The doc was very curious to know what I did. Sticking with it is the plan to see if I can bring the glucose under 100.
 
This stuff is just amazing, isn't it? Low carb, high fat, moderate protein just works to resolve "the diseases of civilization"! And there is some really exciting science going on right now... here are some links I sent my friends & family over the past week about exciting new research. Thought I'd share here too...

First is a new paper just out in November in the British Journal of Medicine (BMJ) about insulin as the earliest possible biomarker for detecting metabolic syndrome, which is the root cause for a host of modern, “lifestyle diseases”, including type 2 diabetes and cardiovascular disease. This is not exactly a “new” thing – in fact it was discovered by the late Dr. Joseph Kraft in the 1970s (I posted about here before), but is now finally being picked up by mainstream medicine: http://openheart.bmj.com/content/openhrt/4/2/e000656.full.pdf

The Kraft insulin assay has been around for a while but few doctors have heard of it. It is similar to the glucose tolerance test, in that it measures response over time after ingesting a glucose drink (but measures insulin response rather than glucose). Why is this important? Because metabolic syndrome can show up in insulin response far earlier than with your body’s glucose response, giving you an earlier start to fix it. In fact, many people with cardiovascular disease may not even have an abnormal glucose response, but will show up on this insulin test. You can actually book your own Kraft test here (comes with the glucose tolerance test w/ insulin): http://www.lifeextension.com/Vitami...ance-Test-with-Insulin-8-specimens-Blood-Test

Next is another new paper out a few weeks ago in the journal Frontiers in Molecular Neuroscience about how ketones and a ketogenic diet increase the NAD+ to NADH ratio: https://www.frontiersin.org/articles/10.3389/fnmol.2017.00377/full

What does this gobbledee-gook mean? A high NAD+/NADH reduces inflammation (inflammation is a culprit in heart disease, cancer, and a lot of other diseases). This ratio decreases over time as we age. What this paper points out is that one reason why ketones may be effective at treating a variety of brain disorders and promoting longevity and health is that the use of ketone bodies for energy greatly reduces the consumption of NAD+ molecules by a factor of 4 over glucose (0.5 NAD+ for beta hydroxybutyrate vs 2 for glucose, per acetyl-CoA molecule), and thus increase NAD+ availability. This has huge implications for both health and lifespan!

Also from the journal Frontiers in Molecular Neuroscience, about the brain - this paper surveys some truly astounding recent research on the root causes of Alzheimer's and cognitive decline as we age ("it's the insulin resistance, stupid!" -- again --... from the carbs) and how ketones, as an alternative energy source for the brain, can protect against this. Yes it is a long read, but pretty easy as far as medical papers go, and you don't have to read the whole thing in order to get a lot out of it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937039/#!po=18.7500

Finally, here is a large observational / epidemiological study that came out last year in the journal Food & Nutrition Research: http://www.tandfonline.com/doi/full/10.3402/fnr.v60.31694 . The key thing with ALL epidemiological studies is that they CANNOT prove causation because multiple factors can influence an outcome. They can ONLY show correlation – which means that they should only be used as a starting point for further research. I always cast a wary eye on these types of studies, because they have been so misused over the past 50 years to push an agenda. But here goes… this study examined food consumption and cardiovascular disease (CVD) in 42 countries, and found that the current mainstream medical advice may be upside down!

Some things they found:

  • High animal fat consumption correlates with raised blood cholesterol (no surprise)
  • High carbohydrate consumption correlates with reduced blood cholesterol (no surprise)
  • Raised blood cholesterol levels correlates with both reduced blood pressure and lower cardiovascular mortality (opposite of medical establishment dogma)
  • Animal fat consumption correlates negatively with high blood pressure, high blood glucose and cardiovascular mortality (ditto)
  • Carbohydrate consumption correlates positively with high blood pressure, high blood glucose and cardiovascular mortality

This is a big study and there is a lot of interesting findings – and lots of charts. I encourage you to read it. From the summary of the results:

“We found exceptionally strong relationships between some of the examined factors, the highest being a correlation between raised cholesterol in men and the combined consumption of animal fat and animal protein (r=0.92, p<0.001). The most significant dietary correlate of low CVD risk was high total fat and animal protein consumption. Additional statistical analyses further highlighted citrus fruits, high-fat dairy (cheese) and tree nuts. Among other non-dietary factors, health expenditure showed by far the highest correlation coefficients. The major correlate of high CVD risk was the proportion of energy from carbohydrates and alcohol, or from potato and cereal carbohydrates.”

And from the conclusion:



“Our results do not support the association between CVDs and saturated fat, which is still contained in official dietary guidelines. Instead, they agree with data accumulated from recent studies that link CVD risk with the high glycaemic index/load of carbohydrate-based diets. In the absence of any scientific evidence connecting saturated fat with CVDs, these findings show that current dietary recommendations regarding CVDs should be seriously reconsidered.”
 
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